Avoid prescribing new medications to older adults without first conducting a medication review Avoid sedatives and sleeping pills (benzodiazepines/sedatives/hypnotics) as the first choice for sleep problems in older adults Avoid antipsychotics as the first choice for behavioral disturbances in older adults with dementia Avoid using antibiotics for asymptomatic bacteriuria in older adults Avoid using antidepressants in older adults without adequate evaluation and consideration of non-pharmacological interventions Avoid using statins for primary prevention in older adults without an individual assessment of benefits and risks