Rationale:
Single-fraction radiotherapy provides the same pain relief as fractionated treatment. It spares patients from prolonged hospital stays, allowing them to spend valuable time at home and with their loved ones.
References:
- Lutz S, et al. Palliative radiotherapy for bone metastases: an ASTRO evidence-based guideline. Int J Radiat Oncol Biol Phys. 2011 Mar 15;79(4):965-76. PMID: 21277118.
- Popovic M, et al. Review of international patterns of practice for the treatment of painful bone metastases with palliative radiotherapy from 1993 to 2013. Radiother Oncol. 2014 Apr;111(1):11-7. PMID: 24560750.
- Sande TA, Ruenes R, Lund JA, Bruland OS, Hornslien K, Bremnes R, Kaasa S. Long-term follow-up of cancer patients receiving radiotherapy for bone metastases: results from a randomised multicentre trial Radiother Oncol. 2009 May;91(2):261-6. doi: 10.1016/j.radonc.2009.02.014. Epub 2009 Mar 21.